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BOTOX is contraindicated within the presence of an infection with the proposed injection web site(s) and in individuals that are hypersensitive to any botulinum toxin merchandise or to any from the components during the formulation.
The consequences of MYOBLOC and all botulinum toxin goods may perhaps distribute from the area of injection to provide signs or symptoms according to botulinum toxin consequences. These signs happen to be documented several hours to months soon after injection. Swallowing and respiratory challenges could be existence threatening and there happen to be studies of death.
The neurotoxin advanced is recovered with the fermentation course of action and purified via a series of precipitation and chromatography steps.
If critical and/or immediate hypersensitivity reactions occur, discontinue even further injection of MYOBLOC and institute appropriate healthcare therapy promptly. Using MYOBLOC in individuals using a regarded hypersensitivity to any botulinum neurotoxin or to any from the excipients (human albumin, sucrose), may lead to a life-threatening allergic reaction.
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Safety and usefulness of BOTOX haven't been founded for the therapy of axillary hyperhidrosis in pediatric individuals under age 18.
The potency models of MYOBLOC are certain to the preparation and Organic exercise assay process utilized. Due to distinctions within the aspects of this assay like the vehicle, dilution plan, and laboratory protocols for numerous potency assays, potency models are not interchangeable with other preparations of botulinum toxin items and, hence, units of Organic action of MYOBLOC can not be when compared to or transformed into models of some other botulinum toxin items assessed with almost every other certain assay process [see Description (11)] .
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